Bivalent
In this context, "bivalent" refers to the fact that Cervarix provides protection against 2 strains of HPV. ( HPV-16 and HP-18)
Glossary
Adjuvant
Pharmalogical agents found within Cervarix (AS04) and Gardasil (amorphous aluminium hydroxyphosphate sulphate) which act in combination with the active ingredient to induce recipient immunity
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Adenocarcinoma
A form of cancer derived from glandular tissue
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Bivalent
In this context, "bivalent" refers to the fact that Cervarix provides protection against 2 strains of HPV. ( HPV-16 and HP-18)
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Carcinoma
A form of cancer derived from epithelial cells
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DNA Recombinant Technology
The process by which genetic material from several organisms is manipulated to produce new or hybrid variations. In the case of Gardasil, the HPV L1 protein genes are introduced into the yeast genome
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Dysplasia
Characterised by all or a combination of the following-
Increase in cell size,
Nuclear abnormalities, including changes to chromatin,
Loss of orientation
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Human Papillomavirus (HPV)
The direct cause of cervical cancer in 93+% of cases
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Liquid Based Cytology (LBC)
A relatively new, advantageous method of cell preparation which removes impurities such as blood from samples for a more conclusive result
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Metaplastic
The ability of a cell to change from one differentiated cell type to another
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Neoplasia
An abnormal, uncontrolled process of cell proliferation